Many of the roads in the U.S. are non-Interstate, local and rural roads that are maintained and operated by local agencies, such as towns, counties, and Tribal governments. Non-motorized modes of travel, such as biking, walking, and riding horses or horse-drawn carriages can be expected along these roads and may face safety concerns when utilizing the same roadway as motorized travelers. This Non-Motorized User Safety Manual focuses on low-volume local rural roadways and rural villages and describes a process that can be used to address the safety of non-motorized users. It provides a concise toolbox of resources and information for addressing non-motorized safety concerns, and provides evaluation methods for locally implemented initiatives to address the safety of non-motorized users.